Hsiang-Hsi Ling, M.S.
Graduate Research Assistant
Hsiang-Hsi Ling (Ph.D. student) received his master's degree at Taipei Medical University in 2017. As a Master's student in Dr. Cheng-Wei Lin's laboratory, Hsiang-Hsi's research mainly focuses on discovering new biomarkers for the prediction of cancer metastasis and elucidating the underlying mechanism with a special focus on the Hippo pathway. He defined the functional roles of how YAP1 reprograms the metabolic behavior of cancer to facilitate the metastasis in metastatic colorectal cancer and identified the key role of the YAP1-GLUT3 signaling axis in reshaping nutrition dependency. (HHLing et al. Theranostics. 2019). As a Ph.D. student in Dr. Giancotti's laboratory, Hsiang-His continues to explore his interests and leverage his knowledge to study the mechanism of tumor dormancy and metastatic reactivation in the multi-step process of tumor metastasis. Currently, his major focus is to understand 1) How Focal Adhesion Kinase transforms the primary mammary epitheliums into malignancy during breast cancer initiation and 2) How Focal Adhesion Kinase facilitates the metastatic outgrowth during tumor dormancy across multiple cancer types.